Cancer has become one of the leading causes of deaths in the west. This has led to the development of various campaigns aiming to find a cure for breast cancer and other common types. Such campaigns are now among the largest businesses in modern medicine. Battling a lethal disease such as cancer is a huge endeavor which entails the best treatments.
In today’s modern world, one of the most powerful treatments for cancer is immunotherapy. The FDA approved the first antibody treatment in 1997. Since then, a dozen more have been approved, widening the range of treatments available to fight cancer.
The development of immunotherapy highly depends on the analysis of genetic data. These data are used by researchers to better understand and develop the cancer treatments. Omixon plays a huge role in this process. Our specialized products help with the study of the Human Leukocyte Antigen genomic region through the use of Next Generation Sequencing data.
Cancer: The Body Working Against Itself
Cancer works in peculiar ways. Though usually triggered by external factors, the cancer itself is caused by the human body’s everyday functions running amok. Bodily processes which have evolved over millions of years to protect us suddenly turn things around; cancer cells begin to grow and spread from our very flesh, working against the genetic coding that maintains order within our body.
There are several types of cancer. But whether it is lung cancer, prostate cancer or ovarian cancer, the disease works basically in the same manner. The genetic material in the affected region changes, which leads to a reduction in the body’s regulation of tissue growth. This can affect the oncogenes responsible for the reproduction and growth of cells. This leads to a rapid growth of cancer cells. Cancer can also be due to the tumor suppressor genes failing to do their job of limiting the lifespan and reproduction of cells to a certain threshold. It only takes one cancer cell to begin this whole process, ultimately leading to various symptoms such as weight loss, internal bleeding, organ failure and death.
Does The Immune System Battle Cancer?
What makes cancer such a deadly disease is its ability to slip through the body’s defense mechanisms. The immune system usually does a great job of detecting foreign elements that pose a threat to the body. But since cancer cells are made by the body itself, the immune system tends to ignore them. Without using modern cancer regimens, the body will have no chance of fighting back.
This is where immunotherapy as well as the support Omixon provides comes in.
What Is Immunotherapy?
Immunotherapy—also called immune enhancement therapy—is a treatment for cancer which works by helping the immune system identify and battle cancer cells.
Antibody therapies are the most successful forms of immunotherapy. Through the use of antibodies, the immune system is able to create proteins which latch onto cells. These antibodies are externally produced. When introduced to the body, they attach to cancer cells and then use different methods to destroy them and ultimately kill the disease. In cell-based therapies, doctors remove immune cells typically from the affected region of the patient. Cancer-fighting cells are then activated, grown outside the patient’s body and re-introduced to the system. This provides the body with the necessary cells that are capable of defeating the elusive cancer cells.
Cancer vaccine is another form of antibody therapy. To stimulate the immune system’s function of fighting diseases, specific cancer antigens can be used. These antigens may be introduced to the surface of T cells, an important part of the immune system which is associated with certain HLA molecules. Depending on the genetic profile of the patient, these antigen-HLA complexes can be used to improve existing cancer vaccines.
Omixon: Cutting Edge Technology For Immunotherapy Development
Omixon focuses on the analysis of the HLA region. Our reagents and software enable scientists to analyze genetic data required for the development of cancer vaccine. This is not only useful for cancer research and determining the intricacies of how the disease works. It helps significantly in identifying the early signs of cancer and providing patients with personalized treatments specifically designed to cater to their needs and fight their particular symptoms.
In order to analyze large amounts of complex data, the latest and most accurate equipment need to be used. Known for using some of the most innovative technologies in the world, our company uses software that allow very accurate analysis and genotyping. Be it running clinical trials, analyzing samples to determine how a patient responds to immune therapy, or performing the most advanced research methods for drug discovery, we can provide the best tools to improve immunotherapy.